Acne Research Today is a free monthly online journal that collates and summarizes the latest research about Acne, including details on skin problems, diet, treatments, puberty.

Dietary glycemic index and glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels in patients with acne.

Kaymak Y, Adisen E, Ilter N, Bideci A, Gurler D, Celik B

Medical Health Center, University of Gazi, Ankara, Turkey. yesimkaymak@yahoo.com

BACKGROUND: Several isolated observations have suggested that acne can develop in groups when a high glycemic index diet is adopted. OBJECTIVE: This study was designed to examine associations among daily diet glycemic index, glycemic loads, serum insulin levels, and acne. METHODS: A total of 49 patients with acne and 42 healthy control subjects were included in the study. At the initial visit, fasting glucose, insulin, insulin-like growth factor-I, insulin-like growth factor binding protein 3, and leptin levels were measured. A voluntary self-completed questionnaire was administered and participants were asked how frequently they consumed the specified amount of food. Overall glycemic index and dietary glycemic load were calculated. RESULTS: No significant differences were observed between patients with acne and control subjects in serum glucose, insulin, leptin levels, overall glycemic index, or dietary glycemic load. LIMITATIONS: The information and data obtained from this questionnaire were limited to patients' own recollections. CONCLUSION: Results of this study indicate that dietary glycemic index, glycemic load, and insulin levels do not have a role in pathogenesis of acne in younger patients.

Published 17 October 2007 in J Am Acad Dermatol, 57(5): 819-23.
Full-text of this article is available online (may require subscription).

© 2004-2008 Acne Research Today. All Rights Reserved.